Highlights and other tweets of the Oomycete Molecular Genetics Network (OMGN) in Toulouse, France, June 2010.
  • "Believe those who are seeking the truth; doubt those who find it." -- French author André Gide /via @wmorgan485 11 June 2010 08:27:31 via Twitterrific

  • RT @widdowquinn #OMGN2010 done... a very good conference. My remaining Twitter followers can relax ;) 9 June 2010 10:34:26 via web

  • #OMGN2010 Oomycete meeting getting closed. OMGN 2011 in Asilomar, California; 2012 in Nanjing, China - Updates at http://pmgn.vbi.vt.edu/ 9 June 2010 10:33:44 via web

  • #OMGN2010 M. Garavito: Extrapolate therapeutic targets from plasmodia to oomycetes such as P infestans; genomics-based search for targets 9 June 2010 10:32:40 via web

  • #OMGN2010 MGaravito: Pinfestans dihydroorotate dehydrogenases target for control; similar to Plasmodium; molecular docking to id inhibitors 9 June 2010 10:32:11 via web

  • #OMGN2010 Badge group photo - http://yfrog.com/j781wj 8 June 2010 17:25:34 via Twitter for iPhone

  • #OMGN2010 Badge group photo - http://yfrog.com/5hd3vj 8 June 2010 17:25:07 via Twitter for iPhone

  • RT @widdowquinn #OMGN2010 - v. exciting controversy over role of RxLRs in translocation 8 June 2010 17:07:20 via web

  • RT @widdowquinn #OMGN2010 Chitin synthases in lipid rafts important for Saprolegnia polarised growth - target for drugs? G. Guerriero 8 June 2010 17:06:45 via web

  • @idjoly You bet! Wawra clearly showed binding in C terminus not RXLR-EER region of AVR3a #OMGN2010 8 June 2010 14:31:45 via Twitter for iPhone in reply to idjoly

  • #OMGN2010 V Phuntumart: There is DNA methylation in Phytophthora after all! Shown by bisulfite treatment and Met-DNA immunoprecipitation 8 June 2010 14:24:24 via Twitter for iPhone

  • #OMGN2010 S Wawra: RXLR effector AVR3a binds phospholipids; effector domain required for binding; RXLR leader DOES NOT bind phospholipids!? 8 June 2010 13:58:17 via Twitter for iPhone

  • #OMGN2010 S Wawra: RXLR-EER leader is a dimerization domain; RXLR-reporter fusions are delivered by dimerizing with native effector 8 June 2010 13:49:43 via Twitter for iPhone

  • #OMGN2010 R Jiang: Fish parasite Saprolegnia parasitica genome: proteases, lectins expanded relative to plant pathogens; disintegrins found 8 June 2010 13:24:43 via Twitter for iPhone

  • #OMGN2010 M Thines: impact of host jumps on effector evolution; dN/dS ratio of 3.2 detected for ATR13; highly polymorphic in pathogen 8 June 2010 11:44:40 via Twitter for iPhone

  • #OMGN2010 Marco Thines: ATR1 and ATR13 sequence diversity in sister species of the downy mildew Hyaloperonospora arabidopsidis (Hpa) 8 June 2010 11:38:48 via Twitter for iPhone

  • #OMGN2010 L Cano: Genome analysis of Phytophthora infestans aggressive clone "blue 13"; Illumina sequence: 9 RXLR effectors missing 8 June 2010 11:28:58 via Twitter for iPhone

  • #OMGN2010 Brett Tyler: Several RXLR effectors of Phytophthora sojae suppress cell death triggered by INF1 elicitin PAMP in N benthamiana 8 June 2010 11:22:48 via Twitter for iPhone

  • #OMGN2010 Walid Hamada: Potato and tomato late blight prevalent in Tunisia; Diverse populations of Phytophthora infestans pathogen 8 June 2010 11:20:27 via Twitter for iPhone

  • #OMGN2010 Brett Tyler: misexpression of RXLR effectors of Phytophthora sojae alters virulence; some activity/expression correlations noted 8 June 2010 11:16:47 via Twitter for iPhone

  • Another "ome" #OMGN2010 http://yfrog.com/7ggxysj 7 June 2010 14:05:26 via Twitter for iPhone

  • RT @widdowquinn #OMGN2010 Controlled recombination for oomycete resistance in brown algae- adaptive immunity? Claire Gachon 7 June 2010 13:56:01 via web

  • #OMGN2010 E Gilroy: Phytophthora infestans RXLR effector AVR3a suppresses the CMPG1-mediated hypersensitive response triggered by Cf9/Avr9 7 June 2010 13:18:39 via web

  • Saprolegnia parasitica genome sequence and gene index at the Broad Institute http://tinyurl.com/3axfcp3 #OMGN2010 7 June 2010 13:08:55 via web

  • #OMGN2010 M Fraiture: Hpa effectors RXLR23 and RXLR31b suppress flg22 elicited PTI; RXLR23 doesnt block MAP kinase activation 7 June 2010 10:58:37 via web

  • #OMGN2010 M Fraiture: screening Hyaloperonosopora arabidopsidis (Hpa) RXLR effectors for PTI suppression using Arabidopsis protoplasts 7 June 2010 10:53:22 via web

  • RT @widdowquinn #OMGN2010 All action at membrane: perihaustorial RXLR effectors and modification of host protein localisation- Seb Schornack 7 June 2010 10:38:24 via web

  • #OMGN2010 S Schornack: clues on RXLR effector functions from cell. localization; focus on perihaustorial effectors, haustoriated plant cells 7 June 2010 10:32:43 via web

  • #OMGN2010 S Schornack: Phytophthora infestans is a hemibiotroph, nice visualization of pathogen and its effectors in plants 7 June 2010 10:29:30 via web

  • #OMGN2010 K Bouwmeester: Arabidopsis lectin receptor kinase AtLecRK-I.9 in potato results in enhanced resistance to Phytophthora infestans 7 June 2010 10:29:02 via web

  • #OMGN2010 Nars: Nod factor receptor NFP involved in bacterial symbiosis also functions in oomycete pathogen interaction; chitin perception? 7 June 2010 10:28:20 via web

  • #OMGN2010 A Nars: Medicago truncatula nfp1/2 RLK mutants enhanced susceptibility to Aphanomyces euteiches, NFP OX causes reduced symptoms 7 June 2010 10:15:16 via web

  • RT @widdowquinn #OMGN2010 NLPs structurally similar to pore-forming toxins but can also be non-cytolytic -> two major families - I. Küfner 7 June 2010 10:14:28 via web

  • Present at both #OMGN2010 & "Beyond Y2K": S Whisson, S Kamoun, D Qutob, M Gijzen, D Cooke, E Huitema, and P Birch http://tinyurl.com/33hy2mk 7 June 2010 09:06:30 via web

  • Present at both #OMGN2010 and "Beyond Y2K" 1999 meetings -from left to right http://tinyurl.com/33hy2mk -S Whisson, S Kamoun, D Qutob etc... 7 June 2010 08:59:09 via web

  • Precursor to #OMGN2010 meetings is "Phytophthora Mol Genetics: Beyond Y2K" Nov 1999 in Wooster Ohio; group photo http://tinyurl.com/33hy2mk 7 June 2010 08:56:31 via web

  • @MPPjournal Think of #OMGN2010 thread as "100 things to know about oomycetes" http://tiny.cc/ya3g0 7 June 2010 08:55:39 via web

  • RT @MPPjournal At this rate Sophien will have to update the paper-Ten things to know about oomycete effectors #OMGN2010 http://tiny.cc/ya3g0 7 June 2010 08:55:20 via web

  • #OMGN2010 Irene de Bruijn: Saprolegnia parasitica genome: many CBEL-like proteins (carbohydrate binding), proteases and protease inhibitors 7 June 2010 08:54:57 via web

  • #OMGN2010 Irene de Bruijn: Genome sequence of the fish pathogen Saprolegnia parasitica released by the Broad; no RXLR, CRN, NLP effectors! 7 June 2010 08:54:44 via web

  • #OMGN2010 S Engelhardt: Recognition of P infestans AVR3a by Solanum R3a requires Sec5, component of exocyst; AVR3a relocalizes R3a 7 June 2010 08:40:50 via web

  • #OMGN2010 S Engelhardt: Recognition of AVR3a by R3a: No Y2H interaction detected but split YFP suggests close association between AVR3a-R3a 7 June 2010 08:39:16 via web

  • LOL, consider it done! RT @widdowquinn #OMGN2010 suggestion for T-shirt for 2011: "XXXX is/is not* RXLR (*delete as applicable) " ;) 7 June 2010 08:35:53 via web

  • RT @widdowquinn #OMGN2010 Neat dissection of structure/phosphorylation/function of CRN8 effector - M van Damme 7 June 2010 08:28:41 via web

  • RT @widdowquinn #OMGN2010 - many interesting questions/proposals about interactions of Avr3a downstream of PAMP detection- A.Chaparro-Garcia 7 June 2010 08:28:07 via web

  • #OMGN2010 Paul Birch (standing in for Susan Breen): Map-based cloning of Phytophthora infestans AVR2; polymorphic; C-term recognized 7 June 2010 08:26:14 via web

  • #OMGN2010 Angela Chaparro-Garcia: Phytophthora infestans RXLR effector AVR3a suppresses PAMP-triggered immunity; multiple functions? 7 June 2010 08:10:09 via web

  • "Oomycetes are not fungi" T-shirt first released in 2000 at MPMI Congress, Madison, Wisconsin; community blossomed in last 10 yrs #OMGN2010 7 June 2010 08:05:04 via web

  • Vintage T-shirt "Bats are not birds, dolphins are not fish, oomycetes are not fungi" spotted at #OMGN2010 http://tinyurl.com/376n8vm 7 June 2010 08:02:10 via web

  • #OMGN2010 Mireille van Damme: Phytophthora infestans secretes a kinase-like protein CRN8 that translocates inside plant cells; active kinase 7 June 2010 07:59:27 via web

  • #OMGN2010 Armstrong Y2H screens: PITG_04314 (RxLRfam49) binds prot phosphatase PP1c; PITG_03192 (RxLRfam66) binds NAC-MTF transcript. factor 7 June 2010 07:52:02 via web

  • #OMGN2010 M Armstrong: in planta localization of 27 RXLR effectors: i cytoplasmic, ii plasma membrane, iii nuclear/nucleolar, iv peroxisome 7 June 2010 07:44:10 via web

  • #OMGN2010 Miles Armstrong: Localization & yeast two hybrid screens with P infestans RXLR effectors to identify targets, understand function 7 June 2010 07:38:55 via web

  • @wmorgan485 sorry about flight delay, hope you make it to #OMGN2010 tomorrow! 6 June 2010 22:46:47 via web

  • RT @widdowquinn AvrL567 structures: http://is.gd/cEO8Q and http://is.gd/cEO9D #OMGN2010 6 June 2010 17:07:48 via web

  • #OMGN2010 M Rep: F oxysporum f sp lycopersici secretes effectors in tomato xylem; Avr2 taken up inside plant cells; recognized by tomato I2 6 June 2010 17:07:10 via web

  • #OMGN2010 Fusarium oxysporum f.sp. lycopersici/tomato system 3 Avr effector-R gene interactions- see Takken & Rep http://tinyurl.com/2vsfhu9 6 June 2010 17:02:47 via web

  • Martijn Rep, Univ of Amsterdam, is the keynote speaker at #OMGN2010 works on fungus Fusarium oxysporum http://home.medewerker.uva.nl/m.rep/ 6 June 2010 16:54:28 via web

  • RT @widdowquinn Assays showing rapid effector entry into human airway cells must worry biologists breathing near Phytophthora ;) #OMGN2010 6 June 2010 16:52:43 via web

  • Rafiqi et al. Plant Cell "Uptake signals in N-termini but sequence not conserved in different rust effectors" http://tinyurl.com/39mompr 6 June 2010 16:18:33 via web

  • Rafiqi et al. Plant Cell "Internalization of flax rust Avr protein into cells occur in absence of pathogen" http://tinyurl.com/39mompr 6 June 2010 16:17:30 via web

  • #OMGN2010 degenerated RXLRs: RXLR -> KXLR -> KXLE -> KALE 6 June 2010 16:16:43 via web

  • #OMGN2010 Shiv Kale: Infiltration of high cc full length RXLR Avr proteins into soybean leaves results in Rps gene dependent cell death 6 June 2010 16:15:38 via web

  • #OMGN2010 Shiv Kale: RXLR-like motif in flax rust AvrL567; bind phospholipid; required for cell uptake; proposes endocytosis uptake process 6 June 2010 16:11:49 via web

  • #OMGN2010 Shiv KALE: degenerate RXLR-like motifs in many effectors from fungi and plasmodia; translocate rapidly into human epithelial cells 6 June 2010 16:04:14 via web

  • #OMGN2010 Shiv KALE: RXLR is very flexible; can be mutated yet still functional in root uptake assay: why is it so highly conserved then??? 6 June 2010 16:01:24 via web

  • RT @widdowquinn Hmp1 joins the long list of comedy gene names that includes PhoQ and SecC #OMGN2010 6 June 2010 15:56:06 via web

  • @fmartin1954 I am hereby tweeting you a virtual cassoulet! #OMGN2010 6 June 2010 15:51:57 via web

  • #OMGN2010 Edgar Huitema: Crinkler LXLFLAK interacting proteins identified; involved in effector translocation? 6 June 2010 15:45:55 via web

  • #OMGN2010 @HuitemaLab_UoD Phytophthora capsici/Nicotiana benthamiana system; haustoria peak in first 48 hrs based on expression of Pchmp1 6 June 2010 15:43:28 via web

  • RT @widdowquinn Have been chastised by @KamounLab at #OMGN2010 for not tweeting enough, these days ;) ---> do it, keeps you awake! 6 June 2010 15:40:05 via web

  • #OMGN2010 Hazel McLellan: Transient RNAi of Phytophthora infestans RXLR effectors: 27 tested, 17 show reduced virulence 6 June 2010 15:32:55 via web

  • #OMGN2010 Daolong Dou's talk illustrates dynamic work on molecular genetics of Phytophthora at Nanjing Ag Univ http://english.njau.edu.cn/ 6 June 2010 15:23:54 via web

  • #OMGN2010 Daolong Dou: P sojae Crinklers cell death requires localization inside plant nuclei; Nuclear Localization Signals required 6 June 2010 15:16:34 via web

  • #OMGN2010 Daolong Dou: Phytophthora sojae Crinklers cause cell death when expressed inside plant cells similar to http://tinyurl.com/3xjtn2o 6 June 2010 15:13:47 via web

  • #OMGN2010 Daolong Dou: Phytophthora sojae Crinklers (w/ signal peptide + LXLFLAK/HVLVVVP motifs); some have Nuclear Localization Signals 6 June 2010 15:10:36 via web

  • #OMGN2010 J Stassen: mining effectors from lettuce downy mildew pathogen Bremia lactucae; screening for suppressors; no results presented! 6 June 2010 15:01:34 via web

  • Qutob: Avr1a 1st case of paramutation Phytophthora gene, but previous report of transgene paramutation http://tinyurl.com/3x9dluo #OMGN2010 6 June 2010 14:55:36 via web

  • Dinah Qutob: Crosses revelaed paramutation as a mechanism to evolve virulence on Rps1a; transfer of silenced state to all progeny #OMGN2010 6 June 2010 14:49:53 via web

  • Dinah Qutob: epialleles in Avr1a effector genes of Phytophthora sojae: identical sequences some expressed others not, crosses made #OMGN2010 6 June 2010 14:45:18 via web

  • 150 participants at the Annual Oomycete Molecular Genetics Meeting, Toulouse, France #OMGN2010 - http://tinyurl.com/3ydxft7 6 June 2010 14:40:41 via web

  • Annual Oomycete Molecular Genetics Meeting kicks off in Toulouse, France #OMGN2010 - http://tinyurl.com/3ydxft7 6 June 2010 14:39:22 via web